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A review of an investigational drug retatrutide, a novel triple agonist agent for the treatment of obesity

Nature (2007) 446(7137):76570

Glutathione Peroxidase 4 Differentially Regulates the Release of Apoptogenic Proteins from Mitochondria Rains, J.L., & Jain, S.K

L.CaiH.EverettR

To construct expression vectors for the secretion of Exe4, double-stranded DNAs of Exe4 fused with signal peptides (SPs) and furin-cleavable sequences were synthesized (Azenta) and inserted into a CAG promoter-containing pCAG backbone vector using the In-Fusion HD cloning kit (Takara Bio)