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Revealingly, one of the first attempts to get an idea on the midpoint potential of the GSH/GSSG couple back in 1952 made use of enzymatic catalysis (Rall and Lehninger, G or Nernst potential E

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The [ 35 S]PAPS synthesized was adjusted to the required concentration and specific activity of 15 Ci/mmol at 1.4 mM by the addition of unlabeled PAPS 17

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