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The fundamental difference is that orlistat prevents absorption of consumed calories from fat, whilst Wegovy reduces the desire to consume calories in the first place and improves metabolic efficiency
Its hard to tell, however, how much of the increase is solely for obesity vs
Lilly also said it saw no heart or liver issues in the data
[PubMed] Roy J, Carrier S
doi: 10.1021/acsnano.2c05558 28 JakubczykKDecKKaduskaJKawczugaDKochmanJJandaK
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