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Despite a significant improvement in the treatment of T2D and CVD over the past few decades, reducing CVD in patients with T2D solely with an optimal glycemic control has been challenging [2]

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Larger structural changes usually relate more to total weight change and time

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Common cycling patterns include standard cycles of 8 weeks on followed by 4 weeks off, extended cycles of 12 weeks on followed by 6 weeks off for more aggressive protocols, and conservative cycles of 6 weeks on followed by 3 weeks off for those preferring a cautious approach

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