The interaction between GLP-1, IELs and gut microbiota highlights its vital role in preserving the integrity of the intestinal mucosal barrier and the gut immunity homeostasis
Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jodar E, Leiter LA, Lingvay I, Rosenstock J, Seufert J, Warren ML, Woo V, Hansen O, Holst AG, Pettersson J, Vilsboll T, SUSTAIN-6 Investigators
These findings indicated that mitophagy was involved in the mechanisms of GLP-1 analog, protecting RGCs under high glucose condition
These findings support the use of microbiome-targeted interventions early in life or illness to potentially mitigate progression of severe psychiatric conditions
2% Diarrhea, vomiting, and abdominal discomfort were also reported more frequently in the semaglutide group