But theyre also a reminder of what sustained investment in basic science can achieve. As UAB researchers continue to study how these drugs work and what comes next, their findings are helping move the conversation beyond hype, while working toward a clearer understanding of one of the most significant medical breakthroughs of the past decade.
Yan Y, Wu T, Zhang M, Li C, Liu Q, Li F
The GLP-1 Receptor Agonist Liraglutide Decreases Primary Bile Acids and Serotonin in the Colon Independently of Feeding in Mice
Healthy Fats: Sustained GLP-1 Through Bile Acid Signaling Dietary fats trigger GLP-1 release through multiple pathways direct activation of fatty acid receptors on L-cells (GPR40 and GPR120), and indirectly through bile acid signaling via the TGR5 receptor
Avoid storing near heat sources, direct light, or in areas with fluctuating temperatures