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As for who is a good candidate for these drugs, there are no official criteria
In people with T2D, 48% of the participants achieved 10% WL after 26 weeks of treatment with orforglipron 45 mg in a phase 2 trial (Fig
It is not that Mounjaro is a stronger medication than Wegovy , but the active ingredient in Mounjaro, tirzepatide, has a dual action because it binds to the receptors of 2 digestive hormones, making it more effective for weight loss
And every forum post, every article, every well-meaning friend has a different theory about what went wrong
Lilly said the latest trial also showed orforglipron improved heart-risk markers, lowering cholesterol, triglycerides and blood pressure across all doses
![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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