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Macromolecule Content Total Structure Weight: 43.93 kDa Atom Count: 3,111 Modeled Residue Count: 370 Deposited Residue Count: 396 Unique protein chains: 1 Experimental Data Method: X-RAY DIFFRACTION Resolution: 2.00 R-Value Work: 0.171 (Depositor), 0.168 (DCC) Unit Cell : Software Package: Revision History (Full details and data files) Version 1.0: 1985-11-08 Type: Initial release Version 1.1: 2008-03-24 Changes: Version format compliance Version 1.2: 2011-07-13 Changes: Advisory, Version format compliance Version 1.3: 2013-12-25 Changes: Non-polymer description Version 2.0: 2017-11-29 Changes: Advisory, Derived calculations, Other, Polymer sequence Version 3.0: 2023-07-26 Type: Remediation Changes: Advisory, Atomic model, Data collection, Database references, Derived calculations, Other, Refinement description
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It is an unapproved research chemical presented here for research and educational purposes only
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Patients who switched from semaglutide to orforglipron maintained a mean 79.3% of their body weight reduction compared with the placebo arm which maintained a mean 37.6% of their weight loss
