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Notably, previous studies have reported that intravenous Exenatide (Exendin-4) infusion does not significantly alter fasting glucagon secretion in humans 39 , supporting the expectation that genome editing-mediated Exe4 secretion would similarly exert minimal disruption

In sharp contrast, neither the negative control (NC) group nor the G/D-CuP group exhibited any discoloration, suggesting hemolysis rates below 5% for these groups

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