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The mainstream theory suggests that chronic inflammation in coeliac disease leads to a leaky gut

[77] Non-ruminant, non-hindgut herbivores may have an enlarged forestomach and/or small intestine to provide a place for bacterial fermentation and B-vitamin production, including B 12

Often, what patients perceive as medication-induced tiredness is actually the body reacting to a sudden drop in sugar and processed carbohydrate consumption

Even so, the chance of it happening is still very, very rare