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However, contrary to the improvements in motor symptoms observed in early clinical trials [52], a recently published large-scale phase 3 clinical trial showed no significant difference after 2 years of exenatide administration compared to placebo [53]
MACE (Major Adverse Cardiovascular Events) : endpoint composito cardiovascolare standard, formato da morte cardiovascolare, infarto miocardico non fatale e ictus non fatale
43,44 Smoking Patients who are current smokers should be encouraged to quit, as smoking increases the risk of pancreatitis
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