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15 When BI2536 was combined with radiotherapy, it inhibited DNA damage repair of U2OS, and also blocked U2OS cells in the G2/M phase, thereby exerting a radiosensitizing effect 16 (Figure 1)

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Its also important to monitor B12 levels periodically through blood tests, as this helps adjust the treatment plan to ensure the best possible outcomes while avoiding over-supplementation

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6,9 However, Arjinpathana and Asawanonda 1 reported many contradictory results regarding the efficacy and safety of glutathione as a skin-lightening agent