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Consequently, our data illuminate a novel role of IGF-1 in regulating stress-induced hepatocyte premature senescence in liver fibrosis: prolonged IGF-1 relieves oxidative stress-initiated hepatocyte premature senescence via inhibition of nuclear p53progerin interaction to ameliorate hepatic steatosis and fibrogenesis

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The Science Behind Glutathiones Role in Skin Health The skin-lightening effects of glutathione stem from its ability to influence melanogenesis, the process by which skin cells produce melanin pigment

doi:10.1001/archpedi.160.9.933