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Umbareen Mahmood, MD, a board-certified plastic surgeon in New York City, says shes now even encountering men and women with already-low BMIs who are using the drugs to lose a few pounds for a big event or beach vacation. Surprisingly, many of these patients are still seeing negative aesthetic side effects, likely due to how rapid the weight loss wasthose who lose weight gradually tend to have better tissue elasticity and skin retractionand also because their margin for loss is smaller given that they were already at a healthy weight for their body. (When someones BMI is low to start, she explains, losing a few pounds can have a significant impact on the little bit of fat you have.) Jerry Chidester, MD, a board-certified plastic surgeon in Draper, Utah, tells me that close to half of his patients are currently using a GLP-1 or have in the past

This suggests some individuals using CagriSema will fare better with a slower, more flexible dose escalation protocol

doi: 10.1111/cpr.13048 45 ZhaoSZhouLWangQCaoJHChenYWangWet al

This natural decrease is a major reason why skin texture changes, color shifts, and wrinkles begin to form as we age

Anecdotal evidence suggests that people taking these drugs could be suddenly drawn to sugary perfumes and scents, possibly even craving them