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Subsequent biochemical and cytochemical studies demonstrated that HGF nitration is maximal in a physiological pH range at Y198 and Y250, characterized by their respective locations at the c-met binding sites of the K1 and K2 domains of the HGF -chain

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When hair is produced by the reproduction of the epithelial cells comprising the follicle, newly produced melanin accumulates in the cells and colors the hair itself as it emerges from the follicle