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While you might experience a small temporary weight gain during the washout week (typically 1-3 pounds), this usually reverses quickly once you start your new medication

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The barrier proteins that should seal moisture in and keep irritants out, like filaggrin and loricrin, get downregulated

Taking drops with food in your stomach

Fatigue Fatigue is often reported during the initial adjustment period and is usually related to changes in caloric intake and blood sugar regulation rather than the medication itself