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Cardiovascular disease Several GLP-1 RAs have demonstrated cardioprotective benefits, including reductions in MACE, heart failure hospitalizations, and progression of atherosclerosis

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Sources include: Parker, C.H., Slattery, C., Brennan, D.J., & le Roux, C.W

However, these studies typically involved healthy volunteers or individuals with prediabetes rather than patients already receiving GLP-1 receptor agonist therapy, limiting direct applicability to the clinical question of combination benefits