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In AD, A damages microglia, produces inflammatory cytokines and chemokines, and affects surrounding CNS resident cells (astrocytes, oligodendrocytes, and neurons), which may aggravate tau pathology and ultimately lead to neurodegeneration and neuron loss
Structural repair (visible on imaging) in 8-12 weeks
Dose escalation typically occurs every 4 weeks
Weeks 1-4: Initial Adaptation Phase Begin with the standard 5-gram daily dose, focusing on timing consistency rather than perfection
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