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The Journal of Nutrition, 134 (3), 489-492

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Mechanistic studies examine its interactions with nitric oxide signaling, prostaglandin pathways, and gastrointestinal dopamine and serotonin turnover, including their relevance to experimental models of intestinal inflammation and gastrointestinal dysfunction

Reactions included nausea, vomiting, chills, low blood pressure, difficulty breathing , and in some cases, possible bloodstream infection