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Eur J Biochem 246:259273 Helmer DA, van Doren WW, Litke DR et al (2020) Safety, tolerability and efficacy of dietary supplementation with concord grape juice in Gulf war veterans with Gulf war illness: a phase I/IIA, randomized, double-blind, placebo-controlled trial

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If your supplement isn't designed for high bioavailability, the timing of your dose might not matter at all because the nutrient may never be absorbed

Like glycine, niacinamide serves as a stabilizer for the peptide structure