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Oxidative stress plays a prominent role in SARS-CoV-2 infection following recognition of the viral S-protein by angiotensin converting enzyme-2 receptor and pattern recognition receptors like toll-like receptors 2 and 4, and activation of transcription factors like nuclear factor kappa B, that subsequently activate nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) expression succeeded by ROS production
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Neuroinflammatory process involved in different preclinical models of chemotherapy-induced peripheral neuropathy
Within the clinical context, the glutathione treatment is commonly used to strengthen the bodys defense against oxidative stress, a cause of early aging and skin dullness
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