The Bottom Line The three growth-hormone peptides sound like a three-way choice, but in practice the decision is between two approaches
With the surge in demand for GLP-1s, online weight-loss programs and telehealth retailers selling compounded versions of Ozempic or similar medications have exploded, seemingly overnight
However, oral formulations represent the most significant route-specific innovation, with the potential to expand the market by addressing injection anxiety and enabling primary care prescribing without specialized training
LY3437943 (retatrutide), a triple agonist at GIP, GLP-1, and glucagon receptors
Additionally, semaglutide is not recommended for individuals with type 1 diabetes or diabetic ketoacidosis, as it is specifically designed for managing type 2 diabetes