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However, the inhibition of tumor cell apoptosis greatly reduces the sensitivity to radiotherapy and impairs its efficacy

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10.1002/advs.202201740 70

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While ERRs are not the canonical thermogenic receptors like PPARs or -adrenergic receptors, their downstream gene networks overlap with brown/brite adipocyte mitochondrial machinery, offering one route for increased energy dissipation under SLU-PP-332 exposure

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