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The suspension was centrifuged at 16,000 g for 10 min at 4 C

The presented transposon-based screen is well-suited to identify attractive targets for potentiators, as gene disruption/silencing can mimic the effect of gene product inhibition with a small molecule 94

Both OAT and PYCR1 are markedly elevated in IPF lung tissues and fibroblasts, with their expression levels correlating with deteriorating lung function and poor prognosis [71, 72]

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