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To reduce the GI side effects, which mainly occur in the early dose escalation period, semaglutide is given in increasing doses by a prefilled pen by self-injection under the skin (abdomen, thigh or arm) starting at 0.25 mg for a month and gradual increases each month reaching the maximum dose of 2.4 mg at month 5
It is also related to other benefits like athletic endurance, weight loss through burning fat, and heart health
During the early titration phase when GI symptoms may limit exercise tolerance, walking is often the only practical option
Hammersmith Health Books
Your provider guides your specific treatment regimen, and you should not change your dosing without discussing it with your provider first
