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The reasoning relates to growth hormone physiology

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Additionally, the body may reduce its resting metabolic rate beyond what would be expected from weight loss alonea phenomenon sometimes called "adaptive thermogenesis." This metabolic compensation means that the same caloric intake that initially produced weight loss may eventually result in weight stability

Flow cytometry-based assay 2 10 5 cells were seeded overnight, collected, and labeled with 1 M FerroOrange dye for 1530 min