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This copper peptide gene regulation manifests in several clinically significant ways: Downregulation of Pro-Inflammatory Genes: It actively suppresses genes associated with inflammation, such as those in the IL-6 and NF-B pathways, which are major drivers of cellular aging
4.2 Obesity-related glucose and lipid metabolism Butyrate supplementation in HFD can prevent HFD-induced elevation of fasting glucose and insulin levels, and improve hyperglycemia and hyperinsulinism (116118, 120122)
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