The drug acts systemically on GLP-1 receptors throughout the body, particularly in the brain, pancreas, and gastrointestinal tract
However, in mold toxicity, systemic immune dysregulation and subsequent inflammation are the underlying mechanisms driving symptoms

In a post on X, Hims & Hers' chief executive, Andrew Dudum, said that the company will "continue to offer access to personalised treatments as allowed by law to meet patient needs," and will be "closely monitoring" the semaglutide supply chain, given that Novo Nordisk "stated two weeks ago that it would continue to have 'capacity limitations' and 'expected continued periodic supply constraints and related drug shortage notifications'." For its part, the FDA said it "has determined the shortage of semaglutide injection products, a glucagon-like peptide 1 (GLP-1) medication, is resolved." The agency will continue to allow compounders to provide semaglutide to patients on a temporary basis "to avoid unnecessary disruption to patient treatment." State-licensed pharmacy or physician compounders can continue to do so until 22nd April, while outsourcing facilities have a deadline of 22nd May
The trigger is a telogen effluvium caused by rapid, significant weight loss
Semaglutide is FDA approved under the brand name Wegovy for weight loss and weight maintenance (along with diet and exercise) in people 12 years and older who have been diagnosed with obesity and in adults who are considered overweight and have at least one weight-related medical condition