Peptide-based therapies for obesity and type 2 diabetes
Unger: Well, there's a lot of discussion out there about weight loss drugs, and so we're going to start with some general background about what the drugs are that are on the market right now and how these drugs work
Central nervous system (brain, retina, and spinal cord) neurodegenerative illnesses impact people of all ages (Figure 1)
With so little direct research, clinical guidelines often lean on what we can reasonably assume from the medication design and its composition, like its size, how the body absorbs it, and how likely it is to pass into breast milk, instead of real-world studies in breastfeeding mothers and babies
This enables Cagri to form conserved interactions when bound to CTR and AMYRs, including the inter-peptide contacts that facilitate the formation and stabilisation of the bypass motif and the intramolecular salt bridge (E14 Cagri and R17 Cagri )