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On Monday, 24th November, Novo Nordisk published a press release, explaining that the Evoke and Evoke+ trials did not confirm superiority of semaglutide versus placebo in the reduction of progression of Alzheimers disease. Although the researchers did report significant reductions in biomarkers associated with Alzheimers, there was no reduction in disease progression in either trial

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doi:10.1158/1055-9965.EPI-09-0871

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These results demonstrate that SPAE effectively reduces DEX-induced DNA damage in hepatic tissues, with the 800 mg/kg dose offering greater genoprotective effects than 400 mg/kg (Table 4

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