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Gastric electrical stimulation (the Enterra device) is FDA-approved under humanitarian device exemption but shows mixed results in clinical trials (McCallum et al., Gastroenterology, 2010)

While some animal studies support clinical observations that these medications also help people reduce or stop alcohol and other drug use, formal human subjects research has yet to be conducted on the relationship between this class of medications and substance use

Archived (PDF) from the original on 4 March 2016

All subjects were enrolled in a standard wound care protocol, where only the subjects with sharp ulcer wound or debridement were entered into this randomized, placebo controlled clinical trial

Gastrointestinal side effects are more likely to occur at the start of treatment or after a recent increase in dose