Peer review Peer review information Nature Chemical Biology thanks Alejandra Tomas and the other, anonymous reviewers for their contribution to the peer review of this work
Limitations & Considerations Much of the published literature on this copper-peptide complex comes from in-vitro and animal-model work rather than large randomized trials, so effect sizes reported in one system do not automatically transfer to another
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However, their use in the perioperative period surrounding major surgeries, like total joint arthroplasty (TJA), remains an area of growing interest and concern
Particles remaining after 5 minutes of gentle swirling are commonly cited as a sign of degraded peptide