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Only high grade NAC promotes whole body skin lightening effect
The tripeptide binds copper with high affinity (log stability constant of 16.44) and delivers it to tissue sites where copper-dependent enzymes (lysyl oxidase, superoxide dismutase, cytochrome c oxidase) drive collagen crosslinking, antioxidant defense, and mitochondrial respiration [1][2]
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Numerically fewer patients reported adverse events such as gynecomastia or agitation, though the differences failed to reach statistical significance, likely in part due to small sample size
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