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Ethics declarations Ethics approval and consent to participate All experiments with brain organoids were performed in accordance with the national and international ethics guidelines, and were approved by the ethics committee at the University of Luxembourg, Comit National dEthique de Recherche (CNER

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Semaglutide is a GLP-1 receptor agonist that enhances glucose-dependent insulin secretion, suppresses appetite via central nervous system pathways, and delays gastric emptying