After 68 weeks, the semaglutide group lost about 13.7 percent of body weight, compared with 3.2 percent on placebo
Steadily, consistently, on its own
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Summary: Retatrutide's long-term side effects are not yet fully established, but current trial data indicate gastrointestinal effects, increased resting heart rate, and potential risks consistent with the GLP-1 receptor agonist drug class
Re-titration may help minimize gastrointestinal side effects when restarting after an interruption