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Arg, Ala, Glu and Tyr were selected as replacements to distinguish the relevance of the charge and size of the side chain and to mimic tyrosine-dependent glutathione transferases 3,18
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It belongs to the family of alpha-hydroxy acids (AHAs) that include the lightest and smallest molecular weight of all acids
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Other evidence implicates NMDA receptors in the interaction between glutathione and glutamate
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