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Preferential fat deposition in subcutaneous versus visceral depots is associated with insulin sensitivity
This specific sequence was first isolated from human plasma in the 1970s, making it a naturally occurring compound that the body already recognizes and utilizes
doi:10.1016/j.soard.2016.02.035 Manna P, Kalita J
Mechanistically, these changes appear to coincide with elevated NAD+ and activation of metabolic gene programs consistent with increased energy expenditure
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