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Because iodine is critical for normal development of the brain, deficiency of this mineral during critical periods, such as during fetal development or during early childhood, can have deleterious effects on cognition

Marino, S., Hogue, I

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2018;8(8):e021944

In parallel, 336 KOs were found to be inversely proportional to the BWG, including those encoding for bacterial biosynthesis of cofactors and amino acids (e.g., phenylalanine, tyrosine, tryptophan, histidine, and lysine), carbon and pyruvate metabolism (including glycolysis/gluconeogenesis, galactose metabolism, and carbon fixation), together with the metabolism of nucleotides (including DNA replication and homologous recombination) and the metabolism of starch and sucrose and fructose and mannose