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The researchers included 30 obese patients in a randomized, double-blind, placebo-controlled, two-period crossover experiment over a 12-week period to accomplish this
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Across 2,783 participants, GLP-1RAs were associated with: - Higher rates of MASH resolution without worsening fibrosis - Reduced liver fat and improved ALT, AST, and GGT levels - Significant decreases in body weight, BMI, waist circumference, HbA1c, and triglycerides While gastrointestinal side effects (nausea, vomiting, diarrhea) were more common, the overall benefit profile was substantial
Injections are administered subcutaneously using a small needle in areas with fatty tissue
