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doi: 10.3390/ijms221910799 6
In AD, mitochondrial abnormalities, including impaired electron transport chain function and reduced mitochondrial biogenesis, lead to increased ROS production and diminished ATP generation
Infertility can occur due to dysfunction of the somatic cells (SCs)
Knockdown of GLS2 but not GLS1 can inhibit cysteine starvation-mediated ferroptosis of MEFs [86]
This effect was mediated by cAMP and PKA and was absent in mice with genetic deletion of the GLP-1R (54)
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