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While lipohypertrophy is well-documented with insulin therapy, it can also occur with GLP-1 receptor agonists like Saxenda, though less frequently
In the Phase 2 trial published in the New England Journal of Medicine, participants receiving the highest dose of retatrutide (12mg weekly) achieved a mean body weight reduction of 24.2% over 48 weeks
Treatment is usually recommended once every 3 months
Estrogens are widely distributed in the body and are generally found in higher concentrations in the sex hormone target organs
Highs will in the mid 90s but it will feel more like 100 degrees
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