In this randomized trial of more than 9300 subjects with T2DM and high cardiovascular risk, liraglutide was seen to decrease the incidence of the composite cardiovascular primary endpoint (occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke) compared with placebo (13.0 and 14.9% in the liraglutide and placebo group, respectively
Never adjust dose independently
Independent of metabolic parameters, DPP4 concentration and activity decrease with HCV clearance and viral treatment
But theres a catch: Although both brand-name medications contain the same GLP-1 agonist, Mounjaro and Zepbound are not approved to treat the exact same conditions
Studies in the National Library of Medicine suggest that GLP-1 medications can improve menstrual regularity and ovulation, reduce insulin resistance and androgen levels, and support spontaneous pregnancy after a period of treatment