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Oxidative stress and intracellular pathway Origin of hepatic fibrosis is initiated by the damage of hepatocytes, resulting in the recruitment of inflammatory cells and platelets, and activation of kupffer cells, with subsequent release of cytokines and growth factors
A., Kamal, M
First, G6PD-derived NADPH is a necessary cofactor for fatty acid synthesis and deficiency in NADPH may therefore lead to impairment and cell death
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