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While motor and cognitive outcomes did not differ significantly from placebo, there was a notable improvement in total NMSS scores, and activities of daily living improved significantly as reflected in MDS-UPDRS Part II scores [57]

Estradiol-induced BAT thermogenesis and its consequent body weight loss can be prevented by activation of AMPK in the VMH (108)

That creates significant regulatory risks

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Based on the only published human study, injectable Ozempic while breastfeeding doesnt appear to pass into milk in detectable amounts