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Potential side effects of semaglutide include: nausea and vomiting diarrhea and constipation stomach pain fatigue hypoglycemia (low blood sugar) acute kidney injury injection-site reactions to injected versions of the drug Overall, semaglutide is also linked to an And its important to remember that when semaglutide is combined with other drugs, additional side effects may occur

(2026) EMC [accessed 15 January 2026] Diabetic retinopathy

Johns Wort can reduce the effectiveness of antidepressants or birth control pills

Avoid smoking and excessive alcohol consumption, as these can deplete glutathione levels

von Richter O, Burk O, Fromm MF, Thon KP, Eichelbaum M, Kivisto KT