Side Effects to Know Some people may feel nausea, stomach upset, constipation, diarrhea or bloating when first starting
Comparative effects among GLP-1 RAs on microbiota Different GLP-1 RA drugs (liraglutide, exenatide, dulaglutide, semaglutide) appear to have broadly similar trends in microbiota modulation, though nuances exist
Some patients report dramatic reduction in hunger by day three, while others experience gradual improvement over two to three weeks
The fact that retatrutide passed its Phase 1 and Phase 2 trials means researchers deemed it safe enough for large-scale human testing
When combined with obstructive sleep apnea (G47.33), the resulting condition OHS is a distinct, more severe diagnosis than OSA alone