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Its positive effects on metabolism were further demonstrated in an animal model of obesity, in which treatment with an alcohol extract of clove reduced the negative impact of a high-fat diet on body weight as well as lipid, glucose, and insulin levels (Jung 2012)

A 2021 randomized controlled trial demonstrated that exenatide, a GLP-1 receptor agonist, significantly slowed cognitive decline in patients with early-stage Parkinsons disease compared to a placebo group (Athauda et al., 2021)

The gene signature that results from canonical ARE activity correlated with improved prognosis

Corrado M, Mariotti FR, Trapani L, Taraborrelli L, Nazio F, Cianfanelli V, et al