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[1] [2] They work by mimicking the action of glucagon-like peptide-1, a naturally occurring hormone produced in the intestine

Maryland Trim Clinic describes GLP-1 medications as slowing stomach emptying, reducing appetite, and increasing fullness, which explains why appetite changes may occur when treatment changes

Slowing gastric emptying is a fundamental part of semaglutides mechanism of action: it keeps food in the stomach longer, prolonging satiety and blunting post-meal blood glucose spikes