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IV zinc may be considered when oral intake is not tolerated, absorption is impaired, or short-term repletion is clinically indicated.

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LPS administration induced significant phosphorylation of NF-B p65 (Ser536), p38 MAPK, and JNK1/2 in lung homogenates

However, people with diabetes may already be at higher risk for low B12 levels due to factors such as age, diet, or certain medications like Metformin