Long-term and more comprehensive studies, as well as analyzes of the molecular mechanisms involved, will be essential for integrating the therapeutic potential of L-carnitine into clinical practice
The stakes are simply too high to accept theoretical risk
Effect of selenium status on thyroid disease Selenium deficiency has been associated with a number of adverse thyroid conditions, including hypothyroidism, subclinical hypothyroidism, enlarged thyroid ( Reference Derumeaux, Valeix and Castetbon 74 Reference Rayman, Duntas, Luster, Duntas and Wartofsky 77 ) , thyroid cancer ( Reference Schmutzler, Mentrup and Schomburg 67 , Reference Rayman, Duntas, Luster, Duntas and Wartofsky 77 Reference Lin, Kuo and Chiang 79 ) and AITD, including HT ( Reference Wu, Rayman and Lv 75 , Reference Rayman, Duntas, Luster, Duntas and Wartofsky 77 ) and GD ( Reference Rayman, Duntas, Luster, Duntas and Wartofsky 77 , Reference Bulow Pedersen, Knudsen and Carle 80 )
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doi:10.1016/j.jmb.2009.03.026